Deterministic effect of lens at leukergy of patients who received low doses of ionising radiation

Manshuk Yeltokova, D. Zharliganova, Mazhit Shaidarov, Meirat Bakhtin, Polat Кazymbet, Tel' Lz, A. Dossakhanov, M. Kozhakbayeva, Masaharu Hoshi

2015

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DOI 10.1093/rpd/ncv296

Data confidence 85 high

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Abstract

To explore the possibility to use the lens extract as an in vitro stimulator to conduct a test of stimulated leukergy in liquidators of the accident consequences (LAC) on Chernobyl Nuclear Power Plant (CNPP) with a cataract in the long-term period. The study sample included 72 men-LAC on CNPP, at the age from 42 to 65 y, who have a cataract. The comparison group consisted of 60 men, with a cataract, of the same age, and who were not exposed to radiation. The control group was composed of 60 men, at the age of 42-58 y without lens pathology. Phenomenon of the stimulated leukergy was revealed in persons who had been exposed to radiation in the dose of 18.2 ± 0.58 cGy and was observed in 5.7-8.05 % (P < 0.001), suggesting a continued high auto-aggression to the lens antigens, and the strength of cell-mediated immunity.