Abstract
Negative environmental conditions of Shymkent increase the risk of lead accumulation in third generation of children, cause the problems with antioxidant protection of respiratory system, significantly reduce barrier-protective properties of cellular systems of tissue immunity, disturb hematopoiesis processes.Statistical data processing enabled us to determine the dependence of lead accretion in soil on the change in functional activity of cheek buccal cells, activity of catalase in expired breath condensate.Both the quantity of reticulocytes and the RPI change correction in accordance with the process of reticulocytes maturation during circulation in peripheral blood as early criterion of toxic anemia refer to haematological symptoms of lead intoxication.