EQUINE HERPESVIRUSES EHV-1 AND EHV-4 IN KAZAKHSTAN

2022

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DOI 10.53729/mv-as.2022.04.03
Data confidence 85 high
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Abstract

В статье представлены современные сведения о герпесвирусах, вызывающих ринопневмонию у лошадей. Приводятся данные о клинических проявлениях болезни, методах диагностики и вакцинопрофилактики. Приведены результаты серологических исследований в ИФА поголовья лошадей Алматинской области - найдены антитела как к EHV-1, так и к EHV-4. Разработанная тест-система для ПЦР позволяет эффективно диагностировать ринопневмонию у лошадей в коневодческих хозяйствах Казахстана. Полногеномное секвенирование местного штамма EHV-1 показало изменения в геноме после аттенуирования штамма методом многократных пассажей в культуре клеток. Contemporary data on equine herpesviruses causing rhinopneumonitis in horses are present in this paper. Data on clinical manifestations, methods of diagnosing and vaccine prophylaxis are given. The results of serological studies of the population of horses in the Almaty region in ELISA are presented - antibodies were found both to EHV-1 and EHV-4. The developed PCR makes it possible to effectively diagnose rhinopneumonitis in horse breeding farms in Kazakhstan. Whole genome sequencing of the local strain EHV-1 showed changes in the genome after strain attenuation after multiple passages in cell culture.