Abstract
Abstract The research was to obtain information and assess the impact of region and seasonal changes on the physical-chemical indicators of milk, as well as to predict the impact of these changes on the composition and quality of products derived from such milk. To assess the differences in milk taken from different regions, as well as to identify the impact of the season on its quality, physical-chemical indicators, including the content of fatty acids in the milk of Holstein cows of the Republic of Kazakhstan were studied. To assess the health status of lactating animals, the content of somatic cells in milk was additionally assessed. The results of studies found that the season and the region significantly influenced the physical-chemical indicators of milk and the content of fatty acids in lipids.