Acid whey valorization: novel approaches for probiotic and functional products development

Frontiers in Nutrition, 2025

Full text Open access: Gold Metadata (CSL-JSON)
DOI 10.3389/fnut.2025.1630925
Data confidence 85 high
How this score is calculated

It is built from checkable properties of the record itself: whether the article has a DOI, how many independent sources confirmed its data, whether the required fields are filled in, and how recent the latest confirmation is. Disagreement between sources and a missing identifier lower it. A value of 80 or above means the record was published without further checking; 60 to 79 means it is published at reduced confidence, with a manual check advisable. A record verified by an editor by hand is never pushed below 90 by a recalculation. This scores our data about the article, not the article itself.

Abstract

Acid whey, a byproduct of dairy processing, particularly from Greek yogurt and cottage cheese production, presents significant environmental and economic challenges due to its high organic load and disposal restrictions. However, the unique composition of acid whey, containing proteins, lactose, minerals, and bioactive compounds, presents promising opportunities for the development of functional, value-added products. This review explores innovative approaches to acid whey valorization, emphasizing biotechnological methods, fermentation techniques, and advanced membrane filtration processes. Comparative analysis of sweet and acid whey compositions underscores specific challenges and advantages in acid whey utilization, various valorization strategies, such as membrane filtration and ultrafiltration, osmosis, enzymatic, and microbial processing, highlighting their effectiveness in ingredient recovery and product development. It also identifies suitable microorganisms capable of efficiently metabolizing acid whey and enhancing the nutritional and functional profiles of derived products. Special attention is given to fermented beverages and other functional products developed from acid whey, incorporating novel strategies to optimize fermentation processes. Moreover, this review details recent advancements in probiotic microencapsulation technologies, demonstrating their effectiveness in maintaining and enhancing probiotic viability in acid whey-based functional beverages. The success of these functional products significantly depends on selecting appropriate probiotic strains, encapsulation materials, and innovative microencapsulation methods. Finally, the article addresses current limitations and outlines future research perspectives, highlighting the potential applications of acid whey-derived products in food, beverages, animal feed, and bioenergy sectors.