Evaluation of a national framework for rational use of medicines in Kazakhstan and its role in improving medicine use practices at the organizational and national levels

Gulzira Zhussupova, Ainur Aiypkhanova, С.С. ЖАЛДЫБАЕВА, Dinara Satmbekova, Tamila Akhayeva, Sholpan Kaliyeva

BMC Health Services Research, 2025

Full text Open access: Gold Metadata (CSL-JSON)
DOI 10.1186/s12913-024-12172-9
Data confidence 85 high
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Abstract

BACKGROUND: Kazakhstan inherited the Semashko health system model, known for the centralized adoption of rules at the Ministry of Health (MoH) level that regulate the healthcare system. In 2019 MoH established a national framework with indicators aimed at collecting qualitative and quantitative data from healthcare organizations as part of their annual self-evaluation, and biannual external evaluation by the National Research Center for Health Development (NRCHD). The purpose of this study was to pilot the MoH framework on rational use of medicines and evaluate its effects on medicine use practices in health care organizations and at the national level. MATERIALS AND METHODS: This cross-sectional study was conducted from October to December 2019 at 22 state-owned primary health care organizations (polyclinics) serving adults and children in Astana, Kazakhstan. Data were collected by trained surveyors visiting each organization. Data were converted to numeric values to arrive at compliance scores for each organization and analyzed to assess each organization's compliance with set indicators. RESULTS: The evaluation showed the rational use of medicines was assessed as "excellent" (90% < compliant) in 2 organizations (9% of the sample), "good" (75-89% compliant) in 7 organizations (32%), and "satisfactory" (50-74% compliant) in 13 organizations (59%), with an average compliance rate of 71% across the sample. 22 organization-specific evaluation reports were developed by the evaluator (NRCHD) and sent to health care organizations for corrective actions. Evaluation data triggered two improvements at the national level: correction of the default setting for trade names to international nonproprietary names within the physician ordering feature of the national health information system for medicines, and adoption of a national policy that allowed the exchange of unused stocks of medicines between polyclinics. CONCLUSIONS: Using the national framework allowed the evaluator agency and healthcare organizations to identify organization-specific gaps and triggered improvements in the use of medicines.