In vitro cytotoxicity and antiviral activity of aminocaproic acid against SARS-CoV-2

Timur M. Saliev, Shynar B. Tanabayeva, Neilya Ussebayeva, Slu Izmailova, Bauyrzhan Umbayev, Gani Akhanov, Nurgulim Akhmad, Ildar Ravisovich Fakhradiyev

2024

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DOI 10.51847/uespvwavbt

Data confidence 70 medium

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Abstract

Since the outbreak of the COVID-19 pandemic caused by the SARS-CoV-2 virus, there has been a pressing need for effective and accessible antiviral agents. Aminocaproic acid (Epsilon-aminocaproic acid, EACA), known primarily for its antifibrinolytic properties, has recently been in the spotlight for its potential cytotoxic and antiviral capabilities. This study aims to evaluate the in vitro cytotoxicity and antiviral activity of EACA against SARS-CoV-2.An in-depth in vitro analysis was conducted i