Terbium-doped Mesoporous Silica Nanoparticles for Bioimaging Purposes

Nurgul Daniyeva, Kamila Zhumanova, Moon Sung Kang, Anara Molkenova, Ki Su Kim, Dong‐Wook Han, Timur Sh. Atabaev

2021

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DOI 10.1109/nanomed54179.2021.9766769
Data confidence 70 medium
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Abstract

In this study, we employed a low-cost and facile soaking method to prepare terbium-doped mesoporous silica nanoparticles (SiO2- Tb NPs) suitable for bioimaging purposes. Morphological analysis showed that prepared silica NPs possess spherical morphology with a mean diameter of ~ 82–1 07 nm. Photoluminescence analysis of SiO2- Tb NPs yielded several luminescent peaks associated with electronic5D4→ 7Fj (where j = 3, 4, 5, 6) transitions within terbium ions. The successful labeling of L-929 cells with SiO2- Tb NPs was tested using a fluorescence microscope. Obtained results suggested that SiO2- Tb NPs can be utilized as promising optically-stable nanoprobes for cells/tissues labeling and imaging.