Supramolecular Complex of 20-Hydroxyecdysone-3-acetate with β-Cyclodextrin and Its Biological Activity

2020

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DOI 10.1134/s1070363220120075
Data confidence 70 medium
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Abstract

Abstract In order to obtain new potentially bioactive substances and to investigate the effect of bulky functional groups on the formation of supramolecular complexes, 20-hydroxyecdysone triacetate has been synthesized, its spatial structure has been determined, and its complexation with β-cyclodextrin has been studied by means of NMR. The anti-inflammatory activity of the obtained water-soluble complex has been assessed.