Abstract
tional PRNT results from 26 sera, of which 18 (69%) were positive, yields a 3.9% positivity rate.In addition to our study, with crude seroprevalence rates ranging from 3.9% to 10.1%, another recent study demonstrated JCV antibodies in 2.9% to 13.3% of ill persons in Massachusetts (Tonry J et al., unpub.data).Although the screening results of our first serosurvey (10.1% positive) differed widely from those of the second serosurvey (3.9% positive), even the lower rate indicates substantial levels of human infection in Connecticut.This report suggests that JCV infection is fairly frequent in Connecticut and that illness may occur, as corroborated by data from neighboring Massachusetts (Tonry J et al., unpub.data) and unpublished laboratory findings from the Connecticut State Public Health Laboratory.The interest in arboviral disease will continue unabated, spurred by the continued occurrence of WNV, and systematic testing for JCV infection may be timely, at least throughout the northeastern United States.