Abstract
Cholera continues to pose a significant public health challenge in Nigeria, driven by poor sanitation, inadequate water quality, and climatic factors that create favorable conditions for outbreaks. Since the first epidemic in 1972, Nigeria has experienced recurrent outbreaks, with the most severe in 1991, resulting in over 7,000 deaths. Current surveillance systems and diagnostic methods are limited by infrastructural gaps, insufficient skilled personnel, and inadequate reporting, leading to delays in outbreak detection and response. These limitations exacerbate the public health burden, increasing mortality and the economic impact of cholera epidemics. This paper explores the potential of artificial intelligence (AI) and machine learning (ML) to address these challenges. AI technologies, including predictive modeling and ML algorithms such as random forests and convolutional neural networks (CNNs), can analyze diverse data sources—such as meteorological, environmental, and health records—to detect patterns and predict outbreaks. Case studies from other cholera-endemic regions, where AI achieved high predictive accuracy, demonstrate its transformative potential. By integrating AI into Nigeria’s public health infrastructure, early detection and response can be improved, resource allocation optimized, and disease transmission minimized. However, challenges such as data quality, standardization, and infrastructural deficits must be addressed. Multi-sectoral collaboration involving public health authorities, AI specialists, and policymakers is essential for the successful deployment of these technologies. This article concludes that AI-powered cholera surveillance systems have the potential to revolutionize public health outcomes, reducing cholera-related morbidity and mortality in resource-limited settings like Nigeria.