A NEW GALLOYLBERGENIN FROM BERGENIA cRASSIFOLIA WITH ANTI-LIPID DROPLET ACCUMULATION ACTIVITY

Hiroshi Morita, Janar Jenis, Liang Fang, Chin Piow Wong, Toshio Kaneda, Yusuke Hirasawa, G. Sh. Burasheva, Abilov Zharylkasyn Abduahitovich

2012

Full text Open access: Gold Metadata (CSL-JSON)

DOI 10.3987/com-12-s(n)110

Data confidence 70 medium

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Abstract

A new bergenin derivative, 3,11-di-O-galloylbergenin (1) was isolated from the roots of Bergenia crassifolia together with four known related compounds.Their structures were elucidated by spectroscopic and chemical analysis.The new galloylbergenin showed a moderate anti-lipid droplet accumulation activity.Bergenia crassifolia (Saxifragaceae) has been used for treatments of bronchitis, gastroenteritis, diarrhea, hemostasia, and metrorrhagia in Kazakh traditional medicine. 1The phytochemical constituents including