Pregnancy outcomes in women with diabetes mellitus – the impact of diabetes type and treatment

2022

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DOI 10.5114/pm.2022.113781
Data confidence 70 medium
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Abstract

Introduction: It has been estimated that approximately 16% of pregnancies worldwide are affected by preexisting or gestational insulin-dependent (type 1) or independent (type 2) diabetes mellitus (DM).Diabetes mellitus in pregnancy remains a high-risk condition for both mother and child.This study aimed to investigate pregnancy outcomes regarding DM types. Material and methods:The study included 323 DM patients delivered for 6 years (2012)(2013)(2014)(2015)(2016)(2017).General and obstetric history data and all complications throughout the pregnancy and the early neonatal period were noted.Based on DM type, women were divided into 4 groups: pre-pregnancy/pre-existing DM, insulin-dependent or independent, and gestational diabetes mellitus with or without insulin therapy.Results: The majority of women had pre-existing insulin-independent DM (type II 62%).Some types of pregnancy/maternal complications were registered in almost 85% of examined pregnancies.However, all babies were live born and mostly with good outcome (36.85% with early neonatal complications).Diabetes mellitus type could not predict the occurrence of neonatal complications (p = 0.342).Pre-existing insulin-dependent DM increased the risk for pregnancy complications (p = 0.031; OR = 1.656).Conclusions: Diabetes mellitus type has a limited impact on pregnancy outcomes and the occurrence of maternal and neonatal complications.With adequate therapy the pregnancy outcome can be good regardless of DM type.