Abstract
The article reveals the main directions of application of the basic provisions, principles and laws of the theory of synergetics in the integration of natural sciences and humanities. Synergetics is an interdisciplinary theory that studies the phenomenon of self-organization. Self-organization is an important condition for the development of living and inanimate nature. The role of synergetics in the integration of academic subjects in the secondary education system, in the formation of students’ holistic worldview about the world around us and in the education of a person with an integrated knowledge system is shown. This interdisciplinary theory is described as a methodological tool necessary to optimize the structure of the content of education.