Abstract
Medicinal plants remain the most important source of bioactive compounds for modern medicine. The genus Rheum is widely used in therapy; however, most research has focused solely on pharmacopoeial species such as R. palmatum. Meanwhile, the rich flora of Kazakhstan possesses significant potential, yet local rhubarb species have not been properly systematised. The aim of this review is to summarise and analyse data on the phytochemical composition and biological activity of Rheum species growing in Kazakhstan in order to assess their prospects as sources of new medicinal substances.