Alkaloid contents and biological activities of Genista lydia Boiss.

Temine Şabudak, Merve Argon, Cansel Çakır, Mehmet Öztürk, MUAZZEZ GÜRGAN ESER, Hilmican Çalışkan

2026

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DOI 10.1080/14786419.2026.2686982
Data confidence 85 high
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Abstract

This study aimed to investigate the biological activities and alkaloid composition of Genista lydia Boiss. (syn. Genista januensis subsp. lydia) growing in the Trakya Region. The plant material was sequentially extracted using chloroform, ethyl acetate, and methanol. The alkaloid composition of the methanolic extract was analyzed by GC–MS. In addition, the extracts were evaluated for their anticholinesterase, antibacterial, tyrosinase-inhibitory, urease-inhibitory, α-glucosidase-inhibitory, and α-amylase-inhibitory activities. GC–MS analysis of the methanolic extract revealed the presence of 14 alkaloid compounds. The major constituents were identified as N-methylcytisine (60.45%), cytisine (22.24%) and anagyrine (13.55%).