Post-Transcriptional Regulation of the Huntingtin Gene by MicroRNAs and PIWI-Interacting RNAs in Neurodevelopment and Neurodegenerative Processes

Engineered Science, 2026

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DOI 10.30919/es2337
Data confidence 70 medium
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Abstract

Ayaz M. Belkozhayev1,2, Email Kamalidin Sharipov2,3 Shara Atambayeva4 Dauren Botbayev1,2 Daulet Sharipov5 Nurlan Jainakbayev6 Altynay Karimova7 Anna Pyrkova4,8 Anatoliy Ivashchenko4,8 Cornelia Wilson9 Yryszhan Zhakypbek10, Email 1Department of Chemical and Biochemical Engineering, Geology and Oil-Gas Business Institute Named After K. Turyssov, Satbayev University, 22 Satbayev Street, Almaty, 050043, Kazakhstan 2M. A. Aitkhozhin Institute of Molecular Biology and Biochemistry, 86 Dosmukhametova Street, Almaty, 050012, Kazakhstan 3Department of Biochemistry, Asfendiyarov Kazakh National Medical University, 94 Tolebi Street, Almaty, 050000, Kazakhstan 4Department of Biotechnology, Faculty of Biology and Biotechnology, Al-Farabi Kazakh National University, 71 Al-Farabi Street, Almaty, 050040, Kazakhstan 5National Laboratory Astana, Nazarbayev University, 53 Kabanbay Batyr Street, Astana, 010000, Kazakhstan 6Department of Public Health, Kazakh Russian Medical University, 51/53 Ablai Khan Street, Almaty, 050000, Kazakhstan 7Department of Biophysics, Biomedicine and Neuroscience, Al-Farabi Kazakh National University, 71 Al-Farabi Street, Almaty, 050040, Kazakhstan 8Center for Bioinformatics and Nanomedicine, 37 Almagul Microdistrict, Almaty, 050040, Kazakhstan 9School of Human and Life Sciences, Canterbury Christ Church University, N Holmes Road, Sandwich, Kent, CT13 9ND, UK 10Department of Surveying and Geodesy, Mining and Metallurgical Institute Named After O.A. Baikonurov, Satbayev University, 22 Satbayev Street, Almaty, 050043, Kazakhstan