Abstract
This study was conducted to investigate histological outcomes of patients with locally advanced colorectal cancer involving the urinary bladder, ureters or prostate. Initial cohort included 45 patients but 10 patients were eliminated from the study due to absence of medical records or non-confirmed colon adenocarcinoma. Finally, the study included 35 patients who underwent colon surgery plus either partial or complete bladder resection, partial ureter resection or prostate resection in time period between 2016 and 2025. Data on patient characteristics and results of histological examination were collected retrospectively. Among patients, who underwent colon surgery plus cystectomy (n=27), only in 48% cases confirmed histological invasion was detected. Overall R0 resection was achieved in 94% cases. These data correspond to literature reviewed findings. True lower urinary tract invasion occurred in approximately half of locally advanced colorectal cancer cases, while en bloc resection achieved high R0 rates, supporting resection when invasion is uncertain.