Assessing Risk Factors in Patients with Chronic Heart Failure and Metabolic Syndrome

Farida Rustamova, А.Б. Альмуханова, Raihan Mukhambetova, Aida Olzhatayeva, Tansholpan Kairat, Nazerke Abdualieva

2026

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DOI 10.4103/wkmj.wkmj_50_26
Data confidence 70 medium
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Abstract

A BSTRACT Background: Chronic heart failure (CHF) is a multifaceted clinical condition that affects over huge number of individuals globally. Precise diagnosis and appropriate management are essential to prevent repeated hospital admissions, lower rates of illness and death, and enhance overall patient outcomes. Aims and Objectives: CHF is a significant medical problem, characterized by high morbidity and mortality, particularly when combined with metabolic syndrome (MS). We compared risk factors associated with the progression to HF in patients with or without with and without metabolic syndrome. Materials and Methods: During a follow-up of 3 months, 35 patients with prior MS and 35 patients without prior MS experienced CHF. Results: In our study, high blood pressure was found to be significantly associated with metabolic syndrome ( P = 0.0062). Patients with chronic heart failure and metabolic syndrome were more likely to have arterial hypertension compared to those without metabolic syndrome. Coronary artery disease was more strongly associated with CHF onset in patients with prior MS (all P for interactions <0.05). The triglyceride level in the MS group was significantly higher only in patients with prior MS (all P for interactions <0.05). Conclusion: The importance of clinical risk factors associated with CHF is dependent on whether the patient has had a prior MS. Coronary heart disease and hypertension are associated with CHF only in the presence of metabolic syndrome. Patients may benefit from early detection and correction of MS risk factors in CHF.