Incidence, Mortality and Five-Year Survival of Colorectal Cancer in the Republic of Kazakhstan (2013–2023)

Dina Toleutayeva, Gulnar SHALGUMBAYEVA, Assel R. Tukinova, Lyazzat Dyussenova, Tolegen Toleutayev

2026

Full text Open access: Gold Metadata (CSL-JSON)
DOI 10.47176/mjiri.40.3
Data confidence 70 medium
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Abstract

Background: Colorectal cancer remains a significant public health concern globally and in Kazakhstan, with rising incidence rates partly attributed to improved screening and lifestyle changes. This study aimed to assess epidemiological trends in colorectal cancer in Kazakhstan from 2013 to 2023, focusing on incidence, mortality, and five-year survival rates. Methods: This population-based registry analysis utilized national cancer registry data on colorectal cancer (CRC) morbidity and mortality. All registered cases from 2013 to 2023 were included. Five-year survival was estimated using aggregated registry data (observed survival). Temporal trends were evaluated using simple linear regression. Results: = 0.008). Mortality decreased notably in the Almaty region, Almaty city, and North Kazakhstan. Five-year observed survival rates for CRC improved from 44.1% to 52.0%, and for rectal cancer from 42.0% to 47.0%. Conclusion: Despite the decline in colorectal cancer mortality in Kazakhstan from 2013 to 2023, the persistently high rate of late-stage diagnoses underscores the urgent need to strengthen early detection efforts and implement region-specific interventions.