Abstract
Allergic diseases, one of the most common non-communicable chronic illnesses in children and adolescents, are characterized by a complex course and heterogeneous genesis. Symptoms of allergic diseases often coexist. It was found that comorbid conditions were observed in 2.9% of adolescents in Naryn and 11.8% of schoolchildren in Manas. Asthma symptoms were reported at some point in time by 17.2% of adolescents in Manas and 3.1% of children in Naryn. The prevalence of allergic rhinoconjunctivitis symptoms among adolescents in Naryn is 13.3%, which is lower than the 38.7% prevalence among schoolchildren in Manas. 4.9% of respondents in Naryn and 18.2% of adolescents in Manas reported having eczema at some point in their lives. The allergy diagnostic method Allergy Explorer2 made it possible to verify polyvalent sensitization, true and cross-reactive allergic sensitization in children with allergic pathology. The international programs Global Initiative for asthma, Global Asthma Network, Allergic Rhinitis and Its Impact on Asthma (2025) recommend the use of combination therapy with inhaled glucocorticosteroids and long-acting β2-agonists, genetically engineered immunobiological drugs for bronchial asthma and combined intranasal sprays with antihistamines and corticosteroids for allergic rhinoconjunctivitis, as well as topical anti-inflammatory, non-steroidal drugs. Implementing educational programs for children and their parents is essential.