Inside Back Cover: Coumarin‐30 Enables Site‐Resolved Detection of Tubulin Ligands by Microscale Thermophoresis (Angew. Chem. Int. Ed. 12/2026)

Mikhail N. Anisimov, Maksim A Boichenko, Anton A. Sivachev, Alexey N. Romanov, Ilya A. Lifshits, Julia N. Borzunova, Marina Janibekova, Vadim V. Mustyatsa, Timur P. Tikhonov, Andrey Yu. Plodukhin

13 more authors

Vitaly V. Shorokhov, Victor A. Tafeenko, Nina K Ratmanova, Sergey S Zhokhov, Роман А. Новиков, Olga I. Kechko, Alexander А. Makarov, Vladimir A. Mitkevich, Ivan A Andreev, Ivan A. Vorobjev, Igor V. Trushkov, Olga A. Ivanova, Никита Борисович Гудимчук

2026

Closed access Metadata (CSL-JSON)

DOI 10.1002/anie.2026-m1902093200

Data confidence 70 medium

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Abstract

In the Research Article (e17086), Igor V. Trushkov, Olga A. Ivanova, Nikita B. Gudimchuk, and co-workers establish coumarin-30 as a new versatile fluorescent probe for tubulin, enabling site-resolved detection of diverse ligands. The cover presents an artistic scene in which coumarin-30 casts light onto a tubulin dimer suspended in a deep-water environment. Four colored ligands appear bound to the protein, while their chemical structures emerge as corals growing on the shadow, each arising from a distinct binding site. Art by M. Andreeva.