Abstract
Aim. To analyze the trends in the incidence of acute cholecystitis in the Akmola region from 2009 to 2022. Materials and methods. The study is based on a retrospective analysis of data from the Ministry of Health of the Republic of Kazakhstan using the International Classification of Diseases, 10th Revision (ICD10), code K81. To assess incidence dynamics, methods of health statistics and time series analysis were applied. Results and discussion . Between 2009 and 2022, a total of 12,538 patients were hospitalized with acute cholecystitis in the Akmola region. The hospital-based incidence rate decreased from 136.3±4.3 to 106.7±3.8 per 100,000 population (p24 hours after symptom onset) decreased from 68.9 to 36.9 per 100,000, reflecting improved early access to care. Conclusions. The study highlights the need to improve medical approaches to the treatment of acute cholecystitis in the Akmola region. The results indicate the critical importance of early diagnosis and timely hospitalization to reduce complications. There is currently a need for additional research to review existing and develop more effective clinical protocols.