Abstract
Introduction. Ischemic heart disease is one of the leading causes of mortality worldwide, highlighting the importance of implementing accessible and non-invasive screening tools at the population level. This study aimed to assess the feasibility of using heart rate variability parameters obtained from a wearable photoplethysmography-based device to evaluate the risk of ischemic heart disease. Materials and methods. A finger-worn IoT device called «Zhurek» was developed, based on photoplethysmography technology and capable of calculating real-time heart rate variability indices. The measurements obtained from «Zhurek» were compared with data from three lead Holter electrocardiographic monitoring, and machine learning algorithms were applied to datasets collected from angiographically confirmed patients and healthy volunteers. Results. The deviations between the new device measurements and Holter electrocardiography remained within clinically acceptable limits; heart rate variability parameters, particularly low-frequency power, and patient age were identified as key diagnostic indicators for detecting ischemic heart disease. Conclusion. The «Zhurek» device is suitable for large-scale ischemic heart disease risk stratification and may facilitate a shift in healthcare from a reactive, symptom-driven approach to a proactive, prevention-oriented model.