Abstract
The article presents the results of the study of pathological morphological changes developed in the internal organs of 7 carcasses of goats aged up to 3 years with contagious pleuropneumonia, delivered to the Department of “Biological Safety” of the Kazakh National Agrarian Research University in 2022-2023 in order to establish the cause of death. The diagnosis of the disease was made on the basis of clinical symptoms, autopsy results and laboratory tests. The diseased goats were kept together with sheep in the same flock. However, the disease was not registered among sheep and lactating calves. Clinical signs of the disease are characterized by uniformity of manifestation in all goats: increase of body temperature up to 41-42°C, oppression, immobility, when going to the field the animal remains at the end of the herd, loss of appetite, difficulty in breathing, frequent coughing, dry cough, sometimes wet. From the nasal cavities of all sick goats excreted creamy purulent fluid. Some goats had swollen eyelids and creamy purulent discharge. Goats were sick for 5-8 days and 80-90% of sick goats died. Goat carcasses were examined by the method of pathologoanatomical slaughter, internal organs were removed by gutting. Lungs, heart, liver, spleen, lymph nodes, intestinal pieces were taken for histologic examination.The obtained slices were fixed in a solution of neutralized 10% formalin in water and sealed with paraffin. Thin sections were obtained using a semiautomatic microtome and stained with hematoxylin-eosin. The prepared histopreparations were examined under a binocular light microscope. The lungs of all slaughtered goats were found to be affected by fibrinous-necrotic pneumonia, fibrinous pleurisy and pericarditis