SYNTHESIS AND GROWTH-STIMULATING ACTIVITY OF IONIC CARBOXYLIC ACID DERIVATIVES CONTAINING TRIMECAINE MOIETY

Bulletin of Shakarim University Technical Sciences, 2025

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DOI 10.53360/2788-7995-2025-2(18)-56
Data confidence 70 medium
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Abstract

This research presents a synthesis, growth-regulating activity of ionic carboxylic acid derivatives containing trimecaine moiety. The novel ionic substances were synthesized by N-alkylation of trimecaine with iodine-containing carboxylic acids under ultrasound-assisted and microwave irradiation, with results compared to traditional thermal methods. Alternative synthesis methods have shown higher yields in a shorter time than traditional synthesis methods. The synthesized compounds were evaluated for their effects on germination energy and capacity across various varieties and hybrids of sweet sorghum seeds. Notably, promising results were observed in seeds stored for extended periods, where germination activity typically declines. The synthesized ionic compounds outperformed the control in terms of germination energy and capacity across various sorghum seed varieties and hybrids. Furthermore, diluted ionic compound solutions (10-3 wt. %) were more effective in promoting seed growth than more concentrated solutions (10-2 wt. %) and water. Additionally, certain ionic compounds provided better stimulation for specific sorghum seed types compared to the commercially available trimecaine hydrochloride.