Abstract
Abstr а ct. After coming to power in Iran, the Islamic regime declares the country's full independence and rejects Washington's political and economic influence. Iranian students took US Embassy staff hostage in November 1979. After this event, contradictions begin between the two countries and the United States announces the first sanctions against Iran. Currently, America continues the policy of the anti-Iranian sanctions regime in various directions. The purpose and objectives of the study are to study the causes and objectives of US sanctions against Iran; to determine their types and periods, to show the role of the presidents of Iran and the United States during the years of sanctions, and to analyze the impact of sanctions on Iran's political and economic development. Chronological analysis and comparative historical methods were used to study these issues. The scientific novelty of the research lies in the study of the directions and stages of US sanctions against Iran. The practical significance of the study lies in the fact that it makes it possible to predict Iran's foreign policy and the internal situation in the country. Results. Washington's main sanctions are directed against Iran's nuclear program. The political positions of the two heads of state have a certain impact on the relationship. Washington is increasing pressure through sanctions, and the Islamic regime is pursuing a policy of protecting its power by using various methods of resistance. Currently, during D. Trump's second presidential term, the issue of resolving the Iranian nuclear issue is being reviewed.