Abstract
Pulp necrosis, a prevalent condition in endodontics, poses significant challenges in preserving tooth vitality and function. Traditional treatment methods like root canal therapy often focus on managing symptoms and controlling the infection rather than promoting natural tissue regeneration. This article evaluates the effectiveness of stem cell therapy as an innovative approach to treating pulp necrosis. We review recent advancements and clinical trials that explore the regenerative potential of stem cells, including mesenchymal stem cells (MSCs), from various sources. The review highlights the underlying mechanisms of stem cell therapy, such as differentiation and angiogenesis, and compares these to conventional methods in terms of efficacy and patient outcomes. By examining the current state of research, challenges, and future directions, this article aims to provide a comprehensive understanding of how stem cell therapy could revolutionize the treatment of pulp necrosis and improve clinical practice.