Sudden Cardiac Death. TdP (Torsade de pointes) in a Hematology Oncology Patient: a Clinical Case

Ainur Bilmakhanbetova

2023

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DOI 10.56598/2957-6377-2023-1-6-28-33
Data confidence 70 medium
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Abstract

Cardiotoxicity is a term that includes various undesirable cardiovascular events during chemotherapy in hematological cancer patients. Cardiotoxicity can occur both during chemotherapy and at different times after its completion. In clinical practice, oncohematologists often face the manifestation of cardiac arrhythmias and conduction disturbances in patients. Acute drug toxicity is often a drug-induced heart rhythm disorder. The purpose of the report: to discuss the diagnostic features of sudden cardiac death using 24-hour ECG monitoring in a hematological oncology patientThis work examines a clinical case of a patient who underwent inpatient treatment of the underlying disease - acute leukemia. Against the background of chemotherapy treatment, drugs of the anthracycline group, cytostatics, anthrypotic drugs and the broad-spectrum antibiotic were used to treat the underlying disease and its complications. All of these drugs have cardiotoxicity. As a result, a young man with no history of structural heart disease experienced an episode of sudden cardiac death, life-threatening heart rhythm disturbance TdP (Torsade de pointes). The timely installation of Holter made it possible to document the episode of the patient's sudden cardiac death.Prolongation of the QTc interval as a predictor of life-threatening cardiac arrhythmias, diagnostic importance of ECG monitoring in cardiac arrhythmias in patients with hematologic oncology.Keywords: TdP - Torsade de pointes, cardiotoxicity, sudden cardiac death, Holter ECG monitoring, hematology oncology.