Abstract
Pathogenetic basis of diseases associated with exposure to chemical pollution of various environmental objects constitute a violation of the process of adaptation,i.e. change of those or other systems of the body, which are called premorbid (prepathological) conditions, differing from diseases of the predominance of non-specific changes on specific. In this regard, the most important direction of research in the field of human ecology and environmental hygiene is the use of high technologies on the basis of informative non-invasive methods of diagnosis of early changes in human health caused by adverse factors.