Abstract
One of the factors hindering the growth and development of the country’s livestock industry is infectious diseases, among which brucellosis occupies a special place. In this regard, this article presents the results of monitoring the epizootic situation of brucellosis of animals in the Turkestan region, the results of bacteriological and serological laboratory studies of brucella isolates isolated from farm animals, as well as data from the production test of the killed vaccine against brucellosis of animals. Antiepizootic measures for brucellosis infection are reduced to the protection of brucellosis-friendly farms and the rehabilitation of disadvantaged ones and are carried out through a comprehensive simultaneous impact on all links of the epizootic chain. This work is complicated by the susceptibility to brucellosis of many animal species, the presence of a large number of transmission factors of the pathogen, as well as the variability of brucella. The importance of carrying out control measures aimed at preventing the spread of brucellosis among healthy animals through the use of modern drugs is emphasized. In addition, the article presents the results of accumulation and extinction of titers of agglutinins and complement-binding substances in the blood serum of cattle and small cattle immunized with inanimate vaccine. Monitoring of the epizootic situation with infectious diseases is based on a deep understanding of epizootic patterns, features of the clinical course of the disease, biological properties of the pathogen, as well as social and natural factors contributing to the manifestation of the epizootic process. It allows you to identify the causes and epizootic consequences of these changes and makes it possible to carry out a complex of antiepizootic measures in a timely manner.