Abstract
Background: The largest global factor contributing to perinatal mortality and morbidity is preterm birth (PTB). To prevent PTB, cervical cerclage is suggested for pregnant women with short cervixes at high risk of giving birth prematurely. Aim: Evaluate different methods of predicting and preventing spontaneous preterm labor in singleton pregnancies. Methods: English studies from various databases were included, using keywords such as "Spontaneous preterm labor," "Prevention," "Singleton pregnancies," combined with "vaginal progesterone" and "cervical cerclage." The date of end for our narrative review is June 2023. Conclusion: Forecasting and prevention of spontaneous preterm labor in singleton pregnancies is a crucial area of research. By identifying risk factors and implementing preventive measures, healthcare professionals can strive to decline the rate of preterm birth. Continued advancements in medical technology and understanding of the underlying mechanisms will further enhance our ability to forecast and prevent this significant obstetric complication.