NUMERICAL MODELING OF PREMATURE CARDIOVASCULAR AGING

2024

Full text Open access: Gold Metadata (CSL-JSON)
DOI 10.55452/1998-6688-2024-21-4-124-135
Data confidence 70 medium
How this score is calculated

It is built from checkable properties of the record itself: whether the article has a DOI, how many independent sources confirmed its data, whether the required fields are filled in, and how recent the latest confirmation is. Disagreement between sources and a missing identifier lower it. A value of 80 or above means the record was published without further checking; 60 to 79 means it is published at reduced confidence, with a manual check advisable. A record verified by an editor by hand is never pushed below 90 by a recalculation. This scores our data about the article, not the article itself.

Abstract

Cardiovascular aging poses a significant threat to the health and quality of life of individuals, especially those aged 65 years and older. This paper presents a way to predict cardiovascular aging using mathematical modeling. The developed model integrates various physiological and behavioral factors including blood pressure, cholesterol level, body mass index, smoking, physical activity and alcohol. The model is based on the application of iteration and Runge Kutta methods, which allows us to describe the dynamic interaction of these factors over time. Validation of the model was performed based on data from clinical studies of elderly patients' health. The results show that the model has high accuracy in predicting the progression of cardiovascular aging and allows to identify patients with increased risk of cardiovascular diseases. The proposed prediction method may become a valuable tool for physicians, helping to develop personalized prevention and intervention strategies in geriatrics, which, in turn, may improve treatment outcomes and prolong the healthy life of patients. Further refinement of the model parameters and expansion of its application to broader populations are planned for the future.