Polarization-phase laser induced and holographic reconstruction of blood facies polycrystalline architectonics in the diagnosis of long-term consequences of COVID-19

2024

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DOI 10.1117/12.3054874
Data confidence 70 medium
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Abstract

A Jones matrix model of biological fluids dehydrated films (facies) optical anisotropy is proposed. The relationships between the blood facies phase (birefringence) anisotropy parameters and the Jones matrix elements real and imaginary components are determined. The experimental testing results of the blood facies polarization matrix thesiography polycrystalline architectonics method with linear and circular birefringence coordinate distributions reproduction are presented. Integral blood facies phase anisotropy maps are presented. Scenarios changes of 1st - 4th orders central statistical moments, which characterize blood facies phase anisotropy maps are determined and physically analysed. The results of the Jones matrix thesiography method clinical testing is presented. Very good and balanced accuracy level has been achieved in the temporal differentiation of the long-term outcomes of patients who have undergone COVID-19. The prospects for further research using an integrated approach based on polarization analysis of laser-induced auto fluorescent images of supramolecular networks of blood facies are indicated.