EFFECTIVENESS OF MOLECULAR GENETIC METHOD FOR DIAGNOSTICS OF ARACHNOMELIA SYNDROME IN CATTLE

А.А. Turgumbekov, G. Shmanov, Zh. Muslimova, Е. С. Усенбеков

2024

Full text Open access: Gold Metadata (CSL-JSON)

DOI 10.52686/conferencearticle_67597cf177b266.99913690

Data confidence 70 medium

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Abstract

The article presents the results of genotyping DNA samples of Angus and Hereford breeds for the genetic defect, ARACHNOMELIA syndrome. DNA testing of DNA samples of 120 samples of each breed was carried out using the PCR-RFLP analysis method, the efficiency of which was 100%. In both breeds studied, heterozygous carriers of the double nucleotide deletion del [CA] in the coding part of the MOCS1 gene were identified, but the prevalence of the deleterious deletion was low and amounted to 4.1% and 2.5%, in the Angus and Hereford breeds, respectively.