Аннотация
We examined 663 patients who were admitted to the clinic by ambulance, for determine the factors of clinical deterioration and progression of ischemic stroke in the acute period of the first 24-72 hours. Among the patients received in the acute period, a fatal out come occurred in 7.23% (48) patients, men- 45.8% and women - 54.2%.At the time of admission to the hospital, almost 96.7% of patients with acute ischemic stroke had a disorder of consciousness from stunning to coma. The most significant risk factors for the development of ischemic stroke among 663 patients were arterial hypertension - 80.1%, chronic heartfailure - 57.9%, coronary heart disease - 25.5%, atrial fibrillation - 19.5%, type 2 diabetesmellitus 12.5%. In accordance with the international criteria of TOAST (1993), pathogenetic mechanisms of the development of isch- emic stroke have been determined in patients. Atherothrombotic stroke developed in 303 (45.7%), cardioembolic stroke in 185 (27.9%) patients, lacunar stroke in 167 (25.2%) patients, undefined genesis stroke in 8 (1.2%) patients.The progression of neurological deficiency in ischemic stroke is a bad prognostic factor.