Аннотация
Aim. To define efficiency and safety of the combined inhalational and intravenous anesthesia (isoflurane + propofol) in patients operated due to gastrointestinal cancer. Methods. 163 patients who were operated due to gastric cancer (119 patients), cancer of the head of the pancreas (24 patients) and colon cancer (20 patients) were examined. Central circulation parameters, autonomic nervous system status, serum cortisol and glucose levels, bispectral index in patients who underwent inhalational or combined inhalational and intravenous anesthesia were compared. Results. There was no significant difference of the examined parameters in patients who underwent combined inhalational and intravenous anesthesia (isoflurane + propofol) compared to patients in whom only inhalational anesthesia with isoflurane was used. Combination was characterized by less change of the examined parameters compared to baseline levels and prolonged emergence from anesthesia. Conclusion. Combined anesthesia is quite safe and effective if used in oncosurgery.