Effects of Carbon Nanoparticles on Bacteria and Application Potential as Biosensors of Pollution Detection of Ocean Water Carbon Nanoparticles as Antibiotics and Biosensors of Ocean Water

2018

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DOI 10.1109/iciibms.2018.8550011
Достоверность данных 70 средняя
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Аннотация

Bacterial infections have been clinically treated with variety of antibiotics. The excessive use of antibiotic nowadays, however, has caused severe drug resistance by the emergence of bacteria strains. The improper management of antibiotic usage has led to the contamination of the environment that threatens people's life. Therefore, it becomes critical to develop novel antibacterial agents that will reduce the risk of drug resistance to its minimum. As the nanomaterial and nanotechnology find their ways to anchor on nearly every aspect of our daily life, the antibacterial properties of nanoparticles have been studied and have shown promising effect while treating different strains of bacteria. Metal containing nanomaterials, though very effective, may potentially accumulate in human body and become cytotoxic. Recently, carbon nano dots derived from natural product have shown comparable antibacterial effect but are low cytotoxicity to human cells and cost. In this study, bactericidal effect of dates-derived carbon nanoparticles (CNPs) on survival of different gram-negative or gram-positive strains was tested. Dates-derived CNPs exhibited strong antibacterial effect against both gram-positive and gram-negative bacteria. Impressively, complete inhibition in the growth of all bacterial strains used in this research was achieved using as prepared CNPs. Moreover, the as prepared CNP was discovered as a great sensor to detect the pollution in ocean water. In deed, an enzyme kit was developed for the ocean water pollution detection. Thus CNP has great potential as biosensor both in medicine and pollution detection of ocean water.