Аннотация
The article provides a scientific rationale for the use of natural sorbents obtained from plant raw materials by the pyrolysis of plant fiber and considers the prospects for their application in veterinary practice as antidotes for intoxications, as effective sorption agents in the control of mycotoxicoses, and in the treatment of gastrointestinal diseases in animals. An enterosorbent produced by pyrolysis by researchers of K. I. Satbayev University from rice husk and walnut shell was tested in calves with simple dyspepsia to determine its therapeutic efficacy. The pharmacodynamics of the enterosorbent was assessed using clinical, hematological, and biochemical parameters in newborn calves. The enterosorbent was administered at a dose of 1.0 g/kg body weight and given orally to calves as a suspension. The results indicate that the treatment duration in the experimental group was reduced by 24±12 hours compared with the control group. In addition, calves receiving the enterosorbent demonstrated a more pronounced correction and restoration of clinical and laboratory blood parameters to physiological values. In the first (experimental) group, the blood levels of total protein increased by 23.6%, glucose by 55.1%, and urea by 36.6%. In the dynamics of hematological parameters, decreases in hemoglobin, leukocytes, and ESR were observed within reference ranges, indicating attenuation of the inflammatory process. An enterosorbent derived from rice husk and walnut shell may have significant prospects in the комплекс treatment of gastrointestinal diseases in young animals, as it can exert a targeted effect by neutralizing the influence of the etiological factor and preventing the absorption of endotoxins, which requires further in-depth investigation of its pharmacological properties.