Аннотация
In the era of technological modernization, new preventive and therapeutic strategies have been developed for cardiovascular diseases. Speckle tracking studies are no exception. Study objective.To evaluate the values of speckle tracking echocardiography parameters in the diagnosis of left ventricular myocardial dysfunction in perimenopausal women. Materials and methods.This study had a prospective design with a one-year follow-up period. The study included 150 female patients, aged 47 to 53 years, with known hormonal levels, corresponding to the perimenopausal period. The study was conducted at the Clinical Medical Center of the Presidential Administration of the Republic of Kazakhstan, Department of Functional Diagnostics. All tests were performed using IBM SPSS Statistics 20 (IBM, USA) with a 95% confidence level. Study results.All 150 subjects underwent routine echocardiography, after which they were divided into two main groups: 90 women (60%) constituted the cohort of individuals with existing LV diastolic dysfunction, while the remaining 60 women, or 40%, were individuals without existing LV diastolic dysfunction. Speckle-tracking echocardiography was performed.In the study, of the 90 patients with LV diastolic dysfunction based on routine echocardiography, 85 had basal segment systolic dysfunction. This constituted 94.5% of patients. In the remaining 5 patients (5.5%), no regressive changes in systole were detected. In the second cohortof sixty women with no LV diastolic dysfunction on routine cardiac ultrasound, only 50 (83.4%) had normal systolic function on the basal plane. The remaining 16.6% (10 patients) with normal diastolic function on routine echocardiography showed abnormal systole and pre-diastolic pathology on speckle-tracking echocardiography.Conclusions.Routine echocardiography in our study demonstrated that it can often serve as a prognostic tool for the development of systolic myocardial dysfunction in individuals with existing left ventricular diastolic dysfunction. A direct correlation was found between the presence of decreased basal plane indices on speckle-tracking echocardiography. This means it is mandatory and recommended to implement speckle tracking in routine echocardiography as an informative predictor of future adverse cardiovascular events.Keywords:speckle tracking echocardiography, left ventricular diastolic dysfunction, left atrium.