Аннотация
This article discusses the role of bacteriophages in veterinary medicine.The relevance of using preparations based on bacterial viruses against the backdrop of developing antibiotic resistance is gaining momentum. Studies have proven the effectiveness of using both monophages and phage cocktails in animal husbandry. The development of phage preparations should be approached with care, starting with the collection of samples for phage isolation, the study of the biological properties of the isolated phages and their resistance to environmental factors, taking into account the ratio of pathogens and their viruses, the achievement of target bacteria by phages in the body, and the optimization of the method of application of bacteriophage preparations. Phage therapy in poultry farming is recommended for combating the most common infections, such as salmonellosis, campylobacteriosis, and colibacillosis. In cattle, phages are used against staphylococci and staphylococci for the prevention and control of mastitis. Phage therapy has also been widely studied on pig farms, in domestic animals, and as disinfectants in animal husbandry. It is important to note that bacteriophages can use a lysogenic type of replication, in which, after adsorption to the pathogen, the bacteriophage nucleic acid integrates with the genome of the host bacterial cell and forms a prophage, which is then transmitted to subsequent generations of bacteria. Therefore, when developing phage preparations, they should be used with caution to avoid repeating problems with resistance.The article presents information on the isolation of bacteriophages to the causative agent of salmonella abortion in sheep