Аннотация
The article evaluates the biosafety of microorganisms based on the study of the pathogenicity and nature of side effects of a new probiotic strain Lactobacillus paracasei – 010K isolated from koumiss. The paper presents data on the determination of potentially pathogenic signs in vitro, virulence, allergenic and irritant sensitizing effects and the study of toxicological effects. According to the existing classification of strains (Maximum permissible concentrations (MPC) of producing microorganisms, bacterial preparations and their components in the air of the working area Hygienic standards GN 2.2.6.709-98), the new strain of Bifidobacterium crudilactis 7-1C belongs to the 4th hazard class. It can be used to develop biological products in order to increase the vegetation of fish, prevent and treat the aura of fish, improve the microflora of the gastrointestinal tract of the stomach.