DISTURBANCES OF UTEROPLACENTAL BLOOD FLOW DURING EXCESSIVE WEIGHT GAIN IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION

Aiman Kerimkulova, Madina Medubayeva, Natalia Latypova, Ходжаева Зульфия Сагдуллаевна, Akbayan Markabayeva, Riza Nurpeissova

2024

Жабық қол жеткізу Метадеректер (CSL-JSON)
DOI 10.1097/01.hjh.0001022800.52276.82
Деректер сенімділігі 70 орташа
Бұл баға қалай есептеледі

Ол жазбаның өзінің тексерілетін белгілерінен құралады: мақаланың DOI-і бар ма, оның деректерін қанша тәуелсіз дереккөз растады, міндетті өрістер толтырылған ба және соңғы растау қаншалықты жаңа. Дереккөздер арасындағы алшақтық пен идентификатордың болмауы бағаны төмендетеді. 80-нен бастап мән жазбаның қосымша тексерусіз жарияланғанын, 60-тан 79-ға дейін — оның сенімділігі төмен күйде жарияланғанын және қолмен тексеру ұсынылатынын білдіреді. Редактор қолмен тексерген жазбаны қайта есептеу 90-нан төмен түсірмейді. Бұл — мақаланың өзіне емес, ол туралы деректерімізге берілген баға.

Аңдатпа

Objective: To evaluate the effect of excess weight gain on the development of uteroplacental blood flow disorders in pregnant women with chronic arterial hypertension. Design and method: A retrospective study was conducted to observe 257 pregnant women with chronic hypertension (CAH) and 200 pregnant women without hypertension and other conditions leading to increased blood pressure (control group). The study was conducted on the basis of perinatal centers in Astana (Kazakhstan) for 2018-2019. The average weight gain during pregnancy and its possible impact on the development of UPC disorders were studied. Results: The main goal of managing pregnant women with arterial hypertension is to prevent the development of complications in the mother and fetus. One of the reasons for an unfavorable prognosis for the fetus is a violation of the uteroplacental circulation (UPC). When comparing pregnant women with CAH and the control group, a violation of UPC was detected in 28.1% and 1.0% of cases, respectively (p <0.001). The average age of pregnant women with CAH was 32.9±5.7 years, in the control group 31.6±5.6 (p=0.059). The average weight gain was found to prevail in the CAH group of pregnant women with CAH (16.86±3.68 kg) compared to the control group (12.91±2.36 kg, p=0.004). Using binary logistic regression, we analyzed the effect of excess weight gain on the development of UPC impairment. In the control group, excessive weight gain was observed in 21 (10.5%) pregnant women, only 2 (1.0%) in the group with normal weight gain (n=179) subsequently developed UPC. Of the 257 pregnant CAH women, 125 (48.7%) had excessive weight gain and 71 (27.6%) developed UPC abnormalities. However, 131 (50.9%) had normal weight gain and only 1 (0.4%) pregnant women with normal weight gain later developed a UPC disorder. Conclusions: To prevent disturbances of uteroplacental blood flow in pregnant women with chronic arterial hypertension, weight gain is important and therefore strict control of weight gain during pregnancy is necessary, compared with the control group.