Аңдатпа
Purpose: Bacterial meningitis (BM) is characterized by severe clinical manifestations, and significant rate of residual effects. It is continue to be a common cause of morbidity and mortality worldwide In Kazakhstan, according to statistics Consumer Protection Committee (CPC) BM recorded in all regions of the country but this epidemiological data was never been analyzed linked with clinical information. Study's aim: To determine morbidity characteristics of BM in children <14 years in various regions of Kazakhstan during 2014-2015. Methods & Materials: Data obtained from CPC of Kazakhstan for BM was analyze for the country and by region in children <14 years. The introduction of Hib vaccine in 2008 into the national vaccination schedule and during 2010 - 2015 the 13-valent pneumococcal conjugated vaccine (PCV13) was gradually introduced in the country. Applying the methods of modern biomedical statistics: Analysis of extensive performance analysis and intensive indicators. Statistical analysis was performed using Statistics 9.0. Results: N. meningitidis was the most common bacteria, 70% of all cases, followed by pneumococcus, 10-15%,. The highest incidence of BM in 2015, determined in Almaty 24.81%, in Astana 24.05%, but in comparison with the year 2014 these figures decreased to half. In the other regions of the country incidence rates, of disease was absent in 2014, Akmola (0.6%), West Kazakhstan (0.67%), Kyzylorda (1.27%), Mangystau (0.52%), and North Kazakhstan (1.73%). During 2015 a significant increase of incidence of BM was observed compared to 2014 year in Almaty region, from 0.75% to 6.18%. Conclusion: In the Kazakhstan Republic among children <14 year in 2015 compared to the year 2014 established decrease of BM from 5.52% to 4.49% for 100,000 population, while in other regions there is a consistent trend of increased morbidity.