Аңдатпа
Purpose: The main aim of present study is to evaluate the clinical and epidemiological features of meningococcal disease in children under the age of 14 in Astana for 2015. Methods & Materials: It is carried out the retrospective analysis of 109 cases with diagnosis of meningococcal disease, observed at the Muncipal Children's Infectious Hospital, Astana, for 2015. For statistical analysis used program SPSS Statictics 20. Results: Among children<14 years noted rising of the incidence of meningococcal infection in Astana in 2015. The high incidence of MI was registered in the spring (69.4%, p≤0.05), while in the winter and summer periods noted significantly lower incidence, 15.6% and 12.8% respectively. In the analysis of anamnesis, the most incidence is registered in children <5 years: from 1 month up to 1 year 18,3%, 1-2 years old 24%, 2-5 years old 34.8%, whereas in children aged 5-10 years old, the incidence rates were 16.5%, 10-14 years 6,4%. it should be noted, the incidence among male children is much higher, 68.8% of all observed patients are boys (p ≤0,05). Determined, meningococcal meningitis without meningococcemia occurs in 1% of cases and meningococcal meningitis combined with meningococcemia occurs in 40.7%, meningococcal meningoencephalitis combined with meningococcemia occurs in 4.6%, meningococcemia in 54% of cases. Bacteriological investigation were performed in 91% of cases, and in other cases, the diagnosis was based on clinical data. Bacteriological method defined the prevalence of serotype A 78,3%, serotype B were detected in 4,9%, serotype C in 13,7% of patients. Conclusion: Incidence of MI in 2015 was more occured in children younger than 5 years (77%), among patients predominated males 68,8%, among clinical forms most often recorded meningococcemia 53,7%, among serotype landscape often recorded serotype A 78,3%. Routine vaccination against meningococcal infection in the Republic of Kazakhstan is not applyed. The study was conducted in the Republic of Kazakhstan, Astana. We would like to express enormous gratitude to the doctor of Municipal Children's Infectious Diseases Hospital of Astana Azhigulov Zhusupbek, to the head of bacteral laboratory - Volkova Gulnara and hospital staff.