Аңдатпа
Background Cervical cancer is the second most common cancer among women. Cervical cancer screening program was initiated in Kazakhstan in 2008. The National Cervical Screening Program in Kazakhstan currently recommends that sexually active women between 30 and 60 years undergo routine screening every 5 years. Objectives To assess the results of the screening program in East Kazakhstan region from 2008 to 2012. Methods Altogether, 128,168 women aged 30-60 years underwent screening in the East Kazakhstan during the study period. All dichotomous data were presented as proportions. We present the data on the age-adjusted prevalence of cervical cancer using the world population. Results Mean age of women who were screened during the study period was 47.5 years old. Altogether, 3.5% of tests were positive. Among those tests which were positive, 72.3% were CIN1(cervical intraepithelial neoplasia), 24.5-CIN2, 1.7%-CIN3, 0.2% adenocarcinoma in situ (AIS), and 1.2% - invasive cancers. Age-adjusted prevalence for CINI during study period was higher than for other types of cervical dysplasia and was markedly higher in women of 60 years old (5.94). ASIR for CIN2, CIN3 also was higher in women of 60 years old and corresponded to 1.85, 0.14. Opposite to this finding ASIR for AIS was higher in women of 45 years old (0.14). ASIR for invasive cancers was higher in women of 40 years old (0.06). Conclusions Screening for cervical cancer in East Kazakhstan revealed 3.5% of tests to be positive. According to the data, 72.3% of cervical dysplasia in teh region belonged to CIN1 and was markedly higher in women of 60 years old. ASIR for AIS and invasive cancers was higher in young women aged 40-45 years old. Key message Cervical cancer screening was introduced in Kazakhstan in 2008 and the first results suggest that 3.5% of tests were positive.