Аңдатпа
Background.With the high rates of cervical cancer incidence and mortality in Kazakhstan and limited coverage of the national cytological cervical screening program, the alternative methods of screening need to be tested and implemented. This is a pilot study that aims to validate acceptance of the cervical self-sampling device for human papillomavirus (HPV) detection among Kazakhstani women and investigate their perceptions of the comfort, potential advantages, and barriers of the approach.Methods.Two questionnaires and a self-sampling HPV test BGI Sentis was distributed among women attending outpatient gynecological facilities in Astana in January 2025 -June 2025. Ordinal logistic regression and non-parametric tests are used to find the relationships between sociodemographic and medical characteristics and attitudes of women. Results.A total of 34 women were included in the final analysis. 61.8% of participants perceived the self-sampling test as easy to take, 82.4% as unpainful, and 58.9% as not unpleasant. Only 44.1% of respondents are sure they took the sample correctly. For their subsequent cervical cancer examination, 38.2% of respondents would choose the self-sampling method, 58.8% -a gynecologist-taken sample, 3% -a GP-taken sample. Conclusions.Women in Kazakhstan accept HPV self-sampling devices as an efficient and comfortable way to increase coverage of cervical cancer screening. Despite their positive experience with the self-sampling device, participants prefer sampling done by a healthcare professional over self-sampling across the board, with no difference in age, marital status, number of children, or other factors. There could be social, cultural, and economic factors affecting women’s preference for sampling by a doctor that need to be further investigated.Keywords:cervical cancer,precancerous diseases of the cervix,self-collection of material.