Application of autologous stem cells in the treatment of ischaemic cardiomyopathy with heart failure after myocardial infarction

Journal of Stem Cells and Regenerative Medicine, 2025

Толық мәтін Ашық қол жеткізу: Gold Метадеректер (CSL-JSON)
DOI 10.46582/jsrm.2101002
Деректер сенімділігі 70 орташа
Бұл баға қалай есептеледі

Ол жазбаның өзінің тексерілетін белгілерінен құралады: мақаланың DOI-і бар ма, оның деректерін қанша тәуелсіз дереккөз растады, міндетті өрістер толтырылған ба және соңғы растау қаншалықты жаңа. Дереккөздер арасындағы алшақтық пен идентификатордың болмауы бағаны төмендетеді. 80-нен бастап мән жазбаның қосымша тексерусіз жарияланғанын, 60-тан 79-ға дейін — оның сенімділігі төмен күйде жарияланғанын және қолмен тексеру ұсынылатынын білдіреді. Редактор қолмен тексерген жазбаны қайта есептеу 90-нан төмен түсірмейді. Бұл — мақаланың өзіне емес, ол туралы деректерімізге берілген баға.

Аңдатпа

The proposed topic is important because it helps find a lot of problems that happen when cardiovascular diseases are passed on along with fibrosis and the link between stem cells and myocardial regeneration.This study aims to investigate the effectiveness of autologous stem cells in the treatment of post-infarction myocardial changes.Statistical, bibliographic, and bibliosemantic research methods and scientific literature for the last 6 years were used to achieve the purpose.Cardiovascular diseases hold the highest prevalence and mortality rates, second only to the number of accidents.Today, there are many methods in the fight against coronary heart disease.However, drug therapy is the least effective, and instrumental methods are too invasive and entail several complications and side effects.Therefore, conducting detailed research on the impact of stem cells on the myocardium affected by infarction presents a challenge.Stem cell transplantation, which includes autologous bone marrow stem cells, typically leads to noticeable and significant changes in cardiac hemodynamic parameters and rheological properties.The development of autologous bone marrow stem cells during the angiogenesis process substantiates such metamorphoses.In addition, factors such as vascular endothelial growth factor and the whole list of coagulogram indicators may influence these changes.The practical significance of the raised subject is using stem cell therapy as an alternative, less invasive method in the fight against postinfarction myocardial changes.Despite such improvements, Askarov et al .[4] pointed out that the high prevalence of risk factors among populations like Kazakhstan continues to present a challenge in reducing mortality from cardiovascular diseases.This underscores the need for more active preventive measures and modern treatment approaches, such as the management of myocardial infarction and rehabilitation after an acute phase.Kurakbayev [5] emphasized that cardiac stem cell treatment, although controversial, has shown potential in improving heart function after injury, though consensus on its therapeutic mechanism is still evolving.The purpose of the research is to conduct an extensive literature search and scientific analysis on the prevalence of cardiovascular diseases.In particular, the study's goals are to examine the incidence of coronary heart disease and heart failure; to highlight the latest therapeutic technologies in the field of cardiology through cell therapy; to characterise all stem cell growths; to present statistics on mortality and recovery after myocardial infarction; to prove or disprove the efficacy of stem cell therapy; and to describe the effectiveness of stem cell therapy.