Аңдатпа
The aim of this study was to evaluate hematological and biochemical changes in the blood of sheep infected with parasitic diseases compared to clinically healthy animals. Parasitic infections, including helminthiasis and coccidiosis, are widespread among small ruminants and cause significant damage to livestock production by reducing productivity and worsening the general condition of the herd. The study included sheep with laboratory-confirmed parasitic infestation (n = 12) and control animals (n = 12). Hematological studies were conducted to determine the following parameters: red blood cells (RBC), hemoglobin (Hb), hematocrit (PCV), leukocyte formula, erythrocyte sedimentation rate (ESR), as well as biochemical analysis of blood serum (total protein, albumin, globulins, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), glucose, urea, creatinine). The results showed a statistically significant decrease in RBC, Hb, and PCV levels in infected animals, indicating the development of anemic syndrome. Elevated MCV and ESR values indicate the presence of an inflammatory process and compensatory reactions of the body. A significant increase in the total number of leukocytes, lymphocytes, and eosinophils reflects the activation of the immune system in response to parasitic invasion. The biochemical profile of infected sheep was characterized by a decrease in total protein and albumin concentrations, as well as an increase in AST, ALT, and ALP activity, indicating hepatocellular damage. Elevated urea and creatinine levels may be due to impaired kidney function or increased protein catabolism. The data obtained emphasize the importance of comprehensive laboratory diagnostics for the early detection and monitoring of parasitic infections in sheep. Hematological and biochemical parameters can serve as reliable markers of the severity of the pathological process and the effectiveness of therapeutic and preventive measures in veterinary practice.